Primary Intraosseous Carcinoma, Not Otherwise Specified with Ameloblastic Carcinoma Features in a Middle-aged Woman

Primary Intraosseous Carcinoma, Not Otherwise Specified (PIOC, NOS) is an extremely rare neoplasm defined as squamous cell carcinoma in the mandible, presumably from residue of odontogenic epithelium. The diagnosis often challenging, and prognosis poor. treatment choice surgical excision but usually declined for cosmetic reasons. A 41-year-old Melanesian woman with a mass her right jaw since two years ago rapidly growing last six months, accompanied pain. Irregular hard was found mandible. Radiology studies revealed lytic tumors, likely infiltrating. No metastasis found. first biopsy acanthomatous ameloblastoma, second pseudoepitheliomatous hyperplasia. Wide then conducted pathology results PIOC NOS some features ameloblastic carcinoma. This case may arise previous benign precursor. Further genetic information be needed. excision. needs further follow-up. intraosseous carcinoma, not otherwise specified merupakan keganasan odontogenik yang langka. Diagnosisnya sulit dengan buruk. Tata laksana utama adalah bedah eksisi cenderung ditolak karena alasan estetik. Seorang perempuan ras Melanesia usia 41 tahun, mengeluh benjolan rahang kanan sejak dua tahun dan makin membesar terutama 6 bulan terakhir disertai nyeri. Massa tidak teratur batas jelas di mandibula ukuran 10 x 8 4 cm. Pemeriksaan radiologis menegaskan massa infiltratif, tetapi menemukan anak sebar. Biopsi awal menunjukkan biopsi selanjutnya Eksisi luas dilakukan patologi PIOC, sebagian ciri Patologi dari tiga jinak mengalami inflamasi kronis kemudian menjadi ganas. Prognosis masih belum bisa dipastikan.